Inventing the Methods Section

Despite attempts at variation, many new research organizations are canalized into just a handful of forms.

A look inside Issue 09.

What the evolution of scientific methods says about their future.

Since launching in 1869, Nature has evolved from a periodical offering commentary on pigeons to the prestige journal in science. But how did Nature build its reputation, and can it last?

Clinical trials are engines for scientific discovery. Better drugs require not just more trials, but also improved data collection, to create therapeutic feedback loops.

On the 90-year saga of oral phenylephrine.